ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Co(II) metal–organic framework for photocatalytic degradation of organic dyes and application values on neonatal gastrointestinal malformations by blocking cholinergic receptor combined with dexmedetomidine

Rui Zhou, Xiao-Ran You, and Chang-Gang Zhang

Department of Anesthesiology, Children’s Hospital Affiliated To Zhengzhou University, Zhengzhou, China

E-mail: z741227@126.com

Received: 26 October 2020  Accepted: 19 December 2020

Abstract:

In this work, a new Co(II)-containing metal–organic framework (MOF) has been generated through the reaction between 1,3,5-benzenetribenzoate (H₃BTB) and Co(II) salt in the existence of a anthracene based N-donor ligand 9,10-bis(1H-imidazol-1-yl)anthracene (dia), and its chemical formula is [Co₂(μ₃-OH)(dia)(btb)·2H₂O]·EtOH·0.5DMF (1). The photocatalytic experiments show that complex 1 has excellent photocatalytic performance for rhodamine B (RhB) and methyl­ene blue (MB) under the irradiation of visible light. Its application values on the neonatal gastrointestinal malformation surgery was assessed; meanwhile, its detailed mechanism was investigated. Firstly, the enzyme-linked immunosorbent assay detection was carried out and the serum cortisol (Cor) content and epinephrine (E) content was measured after compound treatment. Moreover, the cholinergic receptor relative expression levels on neurons were assessed with real time reverse transcription-polymerase chain reaction (RT-PCR).

Keywords: Co-MOF; Dye degradation; Gastrointestinal; Dexmedetomidine

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-020-01488-5

Chemical Papers 75 (5) 2173–2179 (2021)