ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis and characterization of new secondary benzylamines derivatives of aryl-himachalene

Intissar Ait Lahcen, Youssef Edder, Siham Mallouk, Brahim Boualy, and Abdalah Karim

Equipe de Chimie de Coordination et Catalyse, Département de Chimie, Faculté des Sciences Semlalia, Université Cadi Ayyad, Marrakech, Morocco

E-mail: b.boualy@usms.ma

Received: 9 September 2020  Accepted: 6 February 2021

Abstract:

Abstract

A simple and efficient synthesis of aryl-himachalene benzylamines derivatives from himachalenes, natural sesquiterpenes isolated from essential oil of Cedrus atlantica, via chloromethylation reaction. Various aromatic amines were used to provide the corresponding secondary benzylamines in good yields. The reaction offers a first practical synthetic method for the preparation of a range of sesquiterpenes with benzylamines moiety.

Graphic abstract

Keywords: Benzylamine; Natural; Products; Aryl-himachalene; Chloromethylation

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-021-01563-5

Chemical Papers 75 (7) 3207–3213 (2021)