ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Composites based on graphite oxide and zirconium phthalocyanines with aromatic amino acids as photoactive materials

Yuriy Gerasymchuk, Leili Tahershamsi, Robert Tomala, Anna Wedzynska, Viktor Chernii, Iryna Tretyakova, Izabela Korona-Glowniak, Barbara Rajtar, Anna Malm, Dominika Piatek, and Anna Lukowiak

Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Wroclaw, Poland

E-mail: y.gerasymchuk@intibs.pl

Received: 20 February 2021  Accepted: 5 June 2021

Abstract:

This article is a part of a scientific project focused on obtaining a new type of composite materials that are characterized by singlet oxygen generation upon irradiation with red light, which can be used as antibacterial agents. The composite material is nanoscale graphite oxide (GO) particles covalently bonded to an axially substituted zirconium phthalocyanine complex. For this purpose, two phthalocyanine zirconium complexes, axially mono-substituted with 4-aminosalicylic or 4-aminophthalic acids, were prepared and measured in terms of structure, morphology, and spectroscopic properties. The zirconium phthalocyanines are photosensitizers, and the axial ligands are bridging links connecting the complexes to the GO carrier (due to their terminal amino groups and carboxyl groups, respectively). The axial ligand in zirconium phthalocyanine complexes has a strong influence on the stability and optical properties of composite materials and, consequently, on reactive oxygen species (ROS) generation. In this paper, the effect of composite components (4-aminophthalato or 4-aminosalicylato substituted zirconium phthalocyanine complex as a photosensitizer and graphite oxide as a carrier and modulator of the action of active components) on ROS generation for potential antibacterial use is discussed.

Keywords: Axially monosubstituted zirconium phthalocyanine; Graphite oxide; Optical properties; ROS generation; Antimicrobial activity; Genotoxicity

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-021-01731-7

Chemical Papers 75 (10) 5421–5433 (2021)