Effective study of antibacterial and anticancer profiling: Nyctanthes arbor-tristis functionalized silver–zinc oxide nanocompositeK. Shreema, R. Mathammal, V. Kalaiselvi, and S. Gopi Department of Physics, Sri Sarada College for Women (Autonomous), Salem, India
E-mail: mathammals_shanmugam@yahoo.com Received: 25 June 2022 Accepted: 1 September 2022 Abstract: In materials science, the method of green synthesis is rapid, reproducible, sustainable and ecologically sound in the environment. It has broad range of nanomaterials which includes metal, metal oxide, hybrid and biomaterials. In the present study, the silver–zinc oxide nanocomposite (NCs) using fresh leaf extract Nyctanthes arbor-tristis is synthesized by co-precipitation method. From XRD analysis, the crystalline size of Ag–ZnO NCs is increased from 13.02 to 15.15 nm. The functional groups and chemical bonds of ZnO and Ag–ZnO NCs via the leaf extract Nyctanthes arbor-tristis are investigated using FTIR spectral analysis. Absorbance spectra demonstrate significant shift to larger wavelength (red shift) on increasing Ag due to strong interaction between oxides of zinc and silver. The surface morphology of ZnO and Ag–ZnO NCs is determined by scanning electron microscopy. The elemental composition of ZnO and Ag–ZnO NCs is confirmed by EDX analysis. The zone of inhibition against gram positive and gram negative bacteria is determined by antibacterial activity using agar well diffusion method and outcome of the result is error limit in the inhibition zone for increasing the concentration of silver. The Ag–ZnO NCs shows moderate cell viability against HT-29 cell line using Nyctanthes arbor-tristis leaf extract. Keywords: Nanotechnology; Green synthesis; Nyctanthes arbor-tristis; Co-precipitation method; Antibacterial activity; Anticancer activity Full paper is available at www.springerlink.com. DOI: 10.1007/s11696-022-02469-6
Chemical Papers 77 (1) 185–196 (2023) |
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