ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Green synthesis of metal nanoparticles mediated by a versatile medicinal plant extract

Mina Jamzad, Bahar Mokhtari, and Pantea-Sadat Mirkhani

Department of Chemistry, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran

E-mail: m.jamzad@qodsiau.ac.ir

Received: 6 May 2022  Accepted: 29 August 2022

Abstract:

In this study, iron oxide (Fe₃O₄), cuprous oxide (Cu₂O), and silver (Ag) nanoparticles were synthesized during a simple and green method mediated by the aqueous extract of Froriepia subpinnata. The synthesized nanoparticles were characterized by ultraviolet–visible (UV–Vis) and fourier-transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), and transmission electron microscopy (TEM) techniques. The antimicrobial activity of the synthesized nanoparticles and F. subpinnata aqueous extract was studied against some bacteria and fungi using the disk diffusion method. The Cu₂O and Ag nanoparticles were highly effective against the tested pathogenic microorganisms. The diameter of the inhibition zone by the Cu₂O nanoparticles against Staphylococcus group A was measured to be 18 mm, almost equal to the result obtained using Penicillin-G as a reference. The aqueous extract of F. subpinnata was also evaluated on growth inhibition of cell line A549 by the MTT in vitro assay. The half-maximal inhibitory concentration (IC₅₀) was calculated to be 48.32 ± 0.13 μg.ml⁻¹. Furthermore, the potential of synthesized Fe₃O₄ nanoparticles to adsorb the Azo dye Acid-Red 58 from the aqueous media was satisfactory.

Graphical abstract

Keywords: Metal nanoparticles; Froriepia subpinnata; Anti-microbial; Cytotoxicity; Azo dye

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-022-02465-w

Chemical Papers 77 (3) 1455–1467 (2023)