ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Maximum nucleophilicity principle

Hiteshi Tandon, Ratna Banerjee, and Tanmoy Chakraborty

Women Scientist-C (WISE KIRAN IPR), DST, Delhi, India

E-mail: hiteshitandon@yahoo.co.in

Received: 25 April 2023  Accepted: 4 October 2023

Abstract:

An empirical principle, viz. maximum nucleophilicity principle (MNP), is proposed based on studying the change in nucleophilicity index (∆N) for some basic reactions. It is observed that N_Product > N_Reactant and ∆N ≥ 0 in majority of the reactions. Based on the obtained outcomes, it is revealed that ‘a chemical reaction or any species naturally directs itself towards a state of maximum nucleophilicity and stability’ and this behaviour can be known as MNP. It is believed that MNP could act as a valuable tool in predicting reactive behaviours, tendencies and stable geometries of real as well as hypothetical species.

Keywords: Chemical reactivity descriptors; Maximum hardness principle; Minimum polarizability principle; Minimum electrophilicity principle; Nucleophilicity index; Stability

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-023-03152-0

Chemical Papers 78 (2) 1139–1143 (2024)