ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Bacterial cellulose from mother of vinegar loaded with silver nanoparticles as an effective antiseptic for wound-healing: antibacterial activity against Staphylococcus aureus and Escherichia coli

Ana B. Morales-Cepeda, Abigail M. Díaz-Guerrero, Antonio S. Ledezma-Pérez, Carmen N. Alvarado-Canché, and José L. Rivera-Armenta

Centro de Investigación en Petroquímica, Tecnológico Nacional de México/Instituto Tecnológico de Ciudad Madero, Altamira, Mexico

E-mail: abigail.dg@cdmadero.tecnm.mx

Received: 13 June 2023  Accepted: 10 February 2024

Abstract:

Bacterial cellulose (BC) has gained attention in recent years due to its high purity and multiple applications in the biomedical and pharmaceutical fields, and mothers of vinegar are a promising source of low-cost BC that can be easily obtained from any variety of vinegar. Silver nanoparticles (AgNPs) are known for their antimicrobial activity as well as their use as antiseptics on healing wounds. For this research, BC-AgNPs films were synthesized, and their antibacterial activity against Staphylococcus aureus and Escherichia coli was evaluated. The BC films were obtained from mothers of vinegar from two varieties (apple vinegar and cranberry vinegar) and were used as support for AgNPs at 5, 25, 41, 69, 116 and 324 ppm. All the films added with AgNPs achieved growth inhibition of 99–100% for both bacterial species, exhibiting values of antibacterial effectiveness (R) between 3.37 and 7.72. The BC-AgNPs films presented a slightly higher antibacterial activity against S. aureus, but the difference was negligible, and the composites were effective to inhibit the growth of both bacteria. The results show that the BC-AgNPs films synthesized from mothers of vinegar have potential for wound-healing purposes and that they are effective with silver concentrations as low as 5 ppm.

Graphical Abstract

Keywords: Silver nanoparticles; Bacterial cellulose; Antibacterial activity; Antimicrobial activity; Mother of vinegar

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-024-03366-w

Chemical Papers 78 (6) 3959–3969 (2024)