Silver-decorated and graphene-wrapped MgO ternary composite (Ag–GN@MgO) for the potential inhibition of foodborne bacterial pathogensVarish Ahmad and Mohammad Omaish Ansari Health Information Technology Department, The Applied College, King Abdulaziz University, Jeddah, Saudi Arabia
E-mail: Ahmad.varish@gmail.com Received: 17 January 2024 Accepted: 6 June 2024 Abstract: Antibiotic resistance and the increased incidence of foodborne microbial infections have led to a continuous search for new remedies. Inorganic nanoparticles comprising silver and graphene (GN) have broad-spectrum antibacterial capabilities and can eliminate both Gram-positive and Gram-negative bacterial pathogens. In this study, MgO sheets featuring silver decorations and wrapped in GN (Ag–GN@MgO) were characterized and assessed for its toxic effect on foodborne bacterial pathogens. The synthesized nanocomposite was characterized by analytical techniques scanning electron microscopy (SEM), transmission electron microscopy (TEM), elemental analysis, and elemental mapping. Spherical, stacked sheets of MgO were observed in SEM analysis, and it appears that the random combination of many MgO sheets led to the formation of very large, asymmetrical particles. In GN@MgO, exfoliated MgO sheets and large GN sheets were clearly observed. In contrast, Ag–GN@MgO was observed to contain extra clusters or particles of Ag. Although many particles and sheets were imbedded and difficult to discern, MgO and Ag appear to be attached to the GN sheets. TEM analyses of Ag–GN@MgO showed ultrathin MgO sheets of approximately hexagonal shape, as well as several partially exfoliated but stacked sheets are clearly visible. In addition, the GN sheets and nanosized Ag particles (~ 100 nm) are evenly distributed throughout. The ternary composite Ag–GN@MgO was observed to feature a wider zone of inhibition as a toxic effect against Gram-negative Pseudomonas aeruginosa bacteria than against the Gram-positive bacterium Staphylococcus aureus. Thus, the toxic potential of the synthesized ternary complex (Ag–GN@MgO) could be an alternative strategy to control foodborne Gram-positive and Gram-negative bacterial pathogens. Keywords: Nanocomposite; Foodborne pathogens; Antibacterial; Ag–GN@MgO Full paper is available at www.springerlink.com. DOI: 10.1007/s11696-024-03555-7
Chemical Papers 78 (11) 6563–6572 (2024) |
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