ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis and Reactions of Some New Hydroxymethylene Spirofurobenzopyran Derivatives

A. H. Abdel-Rahman, A. M. Khalil, and E. M. Keshk

Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egypt

Abstract: Claisen condensation of furochromanone derivatives with ethyl formate yielded 6-(hydroxymethylene)furobenzopyran derivatives; these with hydrazine hydrate, phenylhydrazine, hydroxylammonium chloride, malononitrile, and ethyl cyanoacetate afforded furopyrazolobenzopyran, furoisoxazolobenzopyran, and furopyranobenzopyran derivatives.Condensation reaction of furobenzopyran-6-carbaldehyde derivatives with indan-1,3-dione gave furobenzopyranylmethyleneindan-1,3-dione derivatives which gave indanopyridine derivatives on treatment with ammonia. Moreover, condensation reaction with dimedone, pyrazolone, barbituric acid, and thiobarbituric acid yielded oxanthenylfurobenzopyran derivatives, furobenzopyranylmethylenepyrazolones, and furobenzopyranylmethylenebarbituric resp. -thiobarbituric acid.

Full paper in Portable Document Format: 545a324.pdf

Chemical Papers 54 (5) 324–331 (2000)