ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Spectrophotometric Study of Equilibria Complexation of Copper(ll), Zinc(ll), and Iron(lll) with 4-(1H-1,2,4- Triazolyl-3-azo)-2-methylresorcinol and Multicomponent Analysis Determination in Drugs

A. Jimenéz, O. Hernández, F. Jimenéz, J. J. Arias, and J. Havel

Departamento de Química Analŕtica, Bromatología y Toxicologic, Universidad de La Laguna, E-38204 La Laguna

Abstract: Spectrophotometric study of Cu(II), Zn(II), and Fe(III) with 4-(1H-1,2,4-triazolyl-3-azo) -2-methylresorcinol (H₃L) and numerical analysis of data using a general least-squares program LETAGROP-SPEFO yields complexes ZnH₂L, ZnHL, Zn(HL)₂, CuH₂L, CU(HL)₂, FeH₂L, FeH₂L(OH)  and Fe(HL)₂ (charges omitted). The equilibria have been studied at I(NaNO₃) = 0.25 mol dm^-3, 25°C in 40 % methanol. Conditions for multicomponent spefo analysis were found, the determination is optimal at pH approximate to 9, with a good sensitivity, i.e. numerical values of molar absorptivity values ε_i/(dm³ mol^-1 cm^-1) 78400, 39500, and 47800 for Zn(II), Cu(II), and Fe(III), respectively. The reagent was used for the determination of these elements in drugs.

Full paper in Portable Document Format: 486a386.pdf

Chemical Papers 48 (6) 386–392 (1994)