ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Stereoselective Transport of Amino Acids and Peptides through Liquid Membranes

P. Dzygiel and P. Wieczorek

Institute of Chemistry, University of Opole, PL-45 052 Opole

E-mail: Piotr.Wieczorek@uni.opole.pl

Received: 11 April 2001

Abstract: A short review concerning the possibility of stereoselective transport of amino acids, peptides, and their derivatives through liquid membranes is presented. The main scope of this paper is to show the variance of such approach and some difficulties in designing of suitable liquid membranes. The detailed discussion of transport mechanisms and carrier molecule architecture necessary to realization of enantioselective differentiation of amino acids, their derivatives, and peptides is also provided. Two different approaches for this type of separation are described and evaluated. They are as follows: application of chiral organic phase and the use of stereoselective receptors for amino acids and other related compounds transportation.

Full paper in Portable Document Format: 561a24.pdf

Chemical Papers 56 (1) 24–31 (2002)