ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Interactions of ß-Cyclodextrin with 4-Alkylmorpholine N-Oxide Surfactants

K. Kráľová, Ľ. Mitterhauszerová, F. Devínsky, and I. Lacko

Institute of Chemistry, Faculty of Natural Sciences, Comenius University, CS-842 15 Bratislava

Abstract: Interactions of ß-cyclodextrin (CD) with nonionic surfactants of the 4-alkylmorpholine N-oxide type (alkyl = C₉-C₁₆) in aqueous solutions were investigated using the spectrophotometric method with methyl orange and the solubilization method, respectively. Results from both the methods confirmed that the process of surfactant association in aqueous solutions is affected by the formation of water-soluble CD surfactant inclusion complexes. In the presence of CD each phase of this process (i.e. monomers, fractional micelle formation range, micellar zone) is shifted towards higher surfactant concentrations. The ratio Δ CMC/c(CD) expressing the measure of the CD surfactant interaction decreases with prolongation of the alkyl chain. It seems that the CD interacts with the alkyl chain of the surfactant molecule and not with its polar head group.

Full paper in Portable Document Format: 471a51.pdf

Chemical Papers 47 (1) 51–54 (1993)