ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

N,N´-Bis(2-alkoxyphenyl)ureas as By-Products in the Reaction of Tertiary Alcohols with 2-Alkoxyphenyl Isocyanates

F. Gregáň, V. Kettmann, P. Novomeský, and J. Ďurinda

Department of Inorganic and Organic Chemistry, Faculty of Pharmacy, Comenius University, CS-832 32 Bratislava

Abstract: Primary and secondary alcohols are known to react with aryl isocyanates to give arylcarbamates, while tertiary alcohols produce diarylureas. In this work we used two tertiary alcohols, 2-methyl-1-dimethylamino-2-propanol and 1-dimethylaminomethylcyclohexanol, to demonstrate that when reacting with 2-alkoxyphenyl isocyanates a mixture of products was obtained, the 2-alkoxyphenylcarbamates being the main products of the reaction.

Full paper in Portable Document Format: 474a240.pdf

Chemical Papers 47 (4) 240–242 (1993)