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Synthesis of Some Biologically Active Derivatives of 2-Hydroxymethyl-5-hydroxy-4H-pyran-4-one. 2. Synthesis and Biological Properties of S-Substituted 2-Thiomethyl-5-O-acyl Derivatives

M. Veverka

Institute of Biotechnology, Slovak Technical University, CS-812 37 Bratislava

 

Abstract: S-Substituted 2-thiomethyl-5-O-acyl-4H-pyran-4-ones were prepared by substituting bromine of 2-bromomethyl-5-hydroxy-4H-pyran-4-one by sulfur-containing nucleophiles and following acylation of the phenolic group. Products of this synthesis were active against bacteria and yeast and stimulate the growth of plants.

Full paper in Portable Document Format: 463a206.pdf

 

Chemical Papers 46 (3) 206–210 (1992)

Wednesday, June 19, 2024

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