ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

N-Substituted pyridinethiocarboxamides and related-compounds as potential antituberculotics

J. Mollin, K. Polášková, and Ž. Odlerová

Department of Inorganic and Physical Chemistry, Faculty of Natural Palacký University, CS-771 46 Olomouc

Abstract: Pyridine- and pyrazinethiocarboxamides have been acylated with acid anhydrides and added to isocyanates and isothiocyanates. Antimycobacterial activity of the reaction products has been followed. The influence of substituents on antimycobacterial activity of the compounds tested herein has been compared to the analogous dependence obtained with thiobenzamide derivatives.

Full paper in Portable Document Format: 426a811.pdf

Chemical Papers 42 (6) 811–816 (1988)