ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Partitioning behavior of isothiocyanates in the two-phase system 1-octanol water

J. Augustín, Š. Baláž, J. Hanes, and E. Šturdík

Department of Biochemical Technology, Slovak Technical University, CS-8J2 37 Bratislava

Abstract: The distribution kinetics of 20 isothiocyanates in two-phase 1-octanol/ water system was characterized by transport rate parameters relating the flux through the interface to concentration of the solute in the aqueous and the organic compartment (l₁, and l₂, respectively). The parameters were shown to be dependent on the partition coefficient P = l₁,/ l₂ as: log (l₁,/(ms^-1)) = log P - log (ßP + 1) + const log (l₂ /(ms-1)) = - log (ßP + 1) + const const = -4.907, ß= 0.261 Importance of this finding for assessment of distribution of the compounds in biological systems is discussed.

Full paper in Portable Document Format: 413a401.pdf

Chemical Papers 41 (3) 401–405 (1987)