ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Veratrum alkaloids. 33. Rhamnoveracintine - a new glycoalkaloid from Veratrum-album ssp. Lobelianum (BERNH) Suessenguth

D. Grančai, V. Suchá, J. Tomko, and L. Dolejš

Department of Pharmacognosy and Botany, Faculty of Pharmacy, Komenský University, CS-832 32 Bratislava

Abstract: A mixture of alkaloids obtained by ethanolic extraction of the aerial part of Veratrum album ssp. Lobelianum (BERNH.) Suessenguth was separated by countercurrent distribution followed by column chromatography to afford a new alkaloid; its structure was proposed by spectral means from the product of hydrolysis. It was denoted rhamnoveracintine ((20S)-(2-methyl-1 -pyrrolin-5-yl)-5-pregnen-3ß-rhamnoside); it is the first veratrum glycoalkaloid containing rhamnose.

Full paper in Portable Document Format: 406a835.pdf

Chemical Papers 40 (6) 835–838 (1986)