ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Domino synthesis of novel series of 4-substituted 5-thioxo-1,2,4-triazolidin-3-one derivatives

Arash Ghorbani-Choghamarani and Sara Sardari

Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran

E-mail: arashghch58@yahoo.com

Abstract: The efficient synthesis of 4-substituted 5-thioxo-1,2,4-triazolidin-3-one derivatives (4-substituted thiourazoles) via domino combination of thiophosgene, aliphatic or aromatic amines, and ethyl carbazate is presented.

Keywords: thiourazole – thiophosgene – amine – ethyl carbazate – isothiocyanate

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-012-0228-1

Chemical Papers 66 (11) 1078–1081 (2012)