ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
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Semisynthetic cephalosporines. I. An improved synthesis of 5-aryl-2-furancarboxylic acids

Ľ. Janda and Z. Votický

Drug Research Institute, Modra, CS-811 04 Bratislava

 

Abstract:  5-Aryl-2-furancarboxylic acids were prepared in substantially higher yields via oxidation of the corresponding furaldehydes, or by basic hydrolysis of 5-aryl-2-furonitriles. The starting aldehydes were obtained by Meerwein arylation of 2-fural.

Full paper in Portable Document Format: 384a507.pdf

 

Chemical Papers 38 (4) 507–513 (1984)

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