ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

¹H NMR study of N-(o-hydroxybenzyl)iminodiacetic acid and its complexes with lanthanum and lutetium

P. Novomeský, L. Sirotková, and J. Majer

Department of Analytical Chemistry, Faculty of Pharmacy, Komenský University, CS-832 32 Bratislava

Abstract: Dependence of chem. shifts of the ¹H NMR signals of nonlabile protons in N-(o-hydroxybenzyl)iminodiacetic acid (HBIDA) in its D₂O solns. on pD was utilized for investigation of successive dissocn. of 3 protons of the HBIDA functional groups. In the HBIDA anion HL^2-, formation is suggested of a Hy bond between the phenolic group and N atom of the amino group. The formation of LaL, LaL₂, LuL, and LuL₂ complexes was found from the pD dependence of proton chem. shifts in the systems where the ratio of c(La(III)) and/or c(Lu(III)) to c(HBIDA) equals 1:1 and 1:2, resp. In these complexes, the O atoms of 2 carboxylate groups are coordinated, as well as the amino group N atom and O one of the phenolic group. The bonds Lu-N are nonlabile in LuL₂ complex, in the other complexes all coordination bonds were labile. Two mols. of HBIDA bonded to Lu in the LuL₂ complex are equiv., while 2 glycinate rings of each HBIDA mol. are mutually nonequivalent.

Full paper in Portable Document Format: 383a351.pdf

Chemical Papers 38 (3) 351–361 (1984)