ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Preparation and biological activity of substituted 1-[2-(alkylthio)-6-benzothiazolylaminomethyl]-5-phenyl-1,2,3,4-tetrazoles

E. Holbová and M. Uher

Institute of Chemistry, Komenský University, 842 15 Bratislava

Abstract:  By Mannich reaction of 6-amino-2-R-thiobenzothiazoles with formaldehyde and 5-(R¹phenyl)-1,2,3,4-tetrazoles, 1-(2-alkyl-, -aryl-, and -benzylthio-6-benzothiazolylaminomethyl) derivatives of substituted tetrazoles have been prepared. The highest biological activity has been found with 2-ethyl deriva­tives of the prepared compounds.

Full paper in Portable Document Format: 362a253.pdf

Chemical Papers 36 (2) 253–257 (1982)