ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Gas chromatography with ballistic heating and ultrafast cooling of column

Žofia Krkošová, Róbert Kubinec, Helena Jurdáková, Jaroslav Blaško, Ivan Ostrovský, Ladislav Soják, and Jiří Ševčík

Chemical Institute, Faculty of Natural Sciences, Comenius University, Mlynská dolina CH-2, SK-845 45 Bratislava, Slovakia

E-mail: kubinec@fns.uniba.sk

Received: 4 June 2007  Revised: 1 August 2007  Accepted: 19 September 2007

Abstract: An overview of the existing methods for minimization of the analysis time in gas chromatography (GC) is presented and a new system for fast temperature programming and very fast cooling down is evaluated. In this study, a system of coaxial tubes, a heating/cooling module (HC-M), was developed and studied with a capillary column placed inside the HC-M. The module itself was heated by a GC oven and cooled down by an external cooling medium. The HC-M was heated at rates of up to 330 °C min⁻¹ and cooled at the rate of 6000 °C min⁻¹. The GC system was prepared for the next run within a few seconds. The HC-M permits good separation reproducibility, comparable with that of a conventional GC, expressed in terms of relative retention times and peak areas of analytes reproducibilities. The HC-M can be used within any commercial gas chromatograph.

Keywords: fast temperature programming - very fast chromatography - ultrafast cooling - phenols

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-008-0002-6

Chemical Papers 62 (2) 135–140 (2008)