ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Benzothiazole compounds. XVI. Preparation and antimycobacterial activity of N',N'-bis[(2-thioxo-3-benzothiazolinyl)methyl]hydrazides

E. Holbová and Ž. Odlerová

Institute of Chemistry, Komenský University, 816 50 Bratislava

Abstract:  The reaction of 2-mercaptobenzothiazole with formaldehyde and hydrazides of acids resulted in bis derivatives of Mannich bases. The relationship between the formation of bis derivatives and the a effect in hydrazides is explained. The prepared compounds were tested for antimycobacterial activity.

Full paper in Portable Document Format: 343a399.pdf

Chemical Papers 34 (3) 399–403 (1980)