ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Isolation and identification of alkaloids from fruits of Berberis thunbergii DC

B. Brázdovičová, D. Košťalová, J. Tomko, and Hwang Yang Jin

Department of Pharmacognosy and Botany, Faculty of Pharmacy, Komenský University, 880 34 Bratislava

Abstract: Two major bisbenzylisoquinoline alkaloids, isotetrandrine and berbamine, and 3 protoberberine type alkaloids, berberine, palmatine, and jatrorrhizine, were isolated from seeds of B. thunbergii. Berberine and oxyberberine, which is not present in the seeds, were isolated from the pericarp. Identity of the isolated substances was verified by spectral means (IR, UV, and mass spectrometry), optical rotation, and comparison with specimens.

Full paper in Portable Document Format: 342a259.pdf

Chemical Papers 34 (2) 259–262 (1980)