ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis and Characterization of Cobalt(II), Cerium(III), and Dioxouranium(VI) Complexes of 2,3-Dimethyl-1-phenyl-4-salicylidene-3-pyrazolin-5-one Mixed Ligand Complexes, Pyrolytic Products, and Biological Activities

Z. H. Abd El-Wahab, M. M. Mashaly, and A. A. Faheim

Department of Chemistry, Faculty of Science, Al-Azhar University for Girls, Nasr-City, Cairo, Egypt

E-mail: zhabdelwahab@hotmail.com

Received: 7 October 2003  Accepted: 25 June 2004

Abstract: New series of Co(II), Ce(III), and UO2(VI) Schiff base complexes were prepared. The reactions of the Schiff base ligand 2,3-dimethyl-1-phenyl-4-salicylidene-3-pyrazolin-5-one (HL) with the above metals in the presence of LiOH as a deprotonating agent yielded different types of mononuclear complexes. Also, the mixed ligand complexes of 2-aminopyridine, 8-hydroxy-quinoline, and oxalic acid were isolated. All the binary and mixed ligand complexes of Co(II) and Ce(III) have octahedral configuration, while the UO2(VI) complexes have distorted dodecahedral geometries. HL is coordinated to the central metal atom as monoanionic tridentate ONO and/or monoanionic tetradentate ONON ligand. Binuclear Ce(III) complex was prepared pyrolytically through the thermal transformation of the mononuclear complex. All the complexes and the corresponding thermal products were isolated and their structures were elucidated by elemental analyses, conductance, IR and electronic absorption spectra, magnetic moments, ¹H NMR and TG-DSC measurements. HL and some of its metal complexes show higher antibacterial effects than those of some of the investigated antibiotics.

Full paper in Portable Document Format: 591a25.pdf

Chemical Papers 59 (1) 25–36 (2005)