ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

α,β-Unsaturated ketones derived from acetylpyridines. IX. Reaction of pyridine analogs of 1,3,5-triphenyl-2-pyrazoline with N-bromosuccinimide

A. Brádlerová, L. Szücs, J. Ďurinda, and J. Heger

Department of Inorganic and Organic Chemistry, Faculty of Pharmacy, Komenský University, 880 34 Bratislava

Abstract: Pyridine analogs of l1,3,5-triphenyl-2-pyrazoline reacted with N-bromosuccinimide to give, instead of the expected 1,3,5-trisubstituted pyrazoles, 1-p-bromophenyl-2-pyrazolines. The same products were obtained in an independent manner from the isomeric azachalcones and p-bromophenylhydrazine. The identity of the products was proved by means of their oxidation with lead tetraacetate which afforded 1,3,5-trisubstituted pyrazoles. The confirmation of the structure of the isolated products was based on the u.V., i.r., and p.m.r. spectral data.

Full paper in Portable Document Format: 296a795.pdf

Chemical Papers 29 (6) 795–802 (1975)