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Synthesis of substituted benzhydrylamines by Leuckart reaction

J. Kalamár and B. Ryban

Department of Organic Technology, Slovak Technical University, Bratislava

 

Abstract: A modified procedure for the preparation of substituted benzhydrylamines by Leuckart reaction was worked out, benzophenones, formic acid and urea being used as starting materials in the presence of a small amount of nickel catalyst. By this method 17 substances were prepared, 8 of which have not been described. The yield of the respective amines ranged from 50 to 95 %, depending upon the appropriate benzophenone substitution.

Full paper in Portable Document Format: 201a79.pdf (in Slovak)

 

Chemical Papers 20 (1) 79–84 (1966)

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