ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Reaction of quinolinic [2,3-pyridinedicarboxylic] anhydride with thiosemicarbazide

J. Hadáček

Institute of Organic Chemistry of the Masaryk University, Brno

Abstract: Quinolinic anhydride and NH₂CSNHNH₂ in aq. NH₃ (1 hr. at 193°, or 30 min. at 42°) give 1,4-di(β-isoquinolinoyl)thiosemicarbazide, C₁₅H₇O₄N₅S (I), m. 267-8° (Ag salt, sinters 234°, decomp. 243°; Ac deriv., C₁₇H₉O₅N₅S, sinters 200°, m. 200-25°). In boiling Ac₂O the product is 1,4-dinicotinoylthiosemicarbazide, C₁₃H₁₁O₂N₅S (tri A g salt; tri-A c deriv., C₁₉H₁₇O₅N₅S). Reaction did not occur in C₆H₆ or PhMe.

Full paper in Portable Document Format: 18a247.pdf (in Slovak)

Chemical Papers 1 (8) 247–252 (1947)