ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis, characterisation, and antioxidant study of Cr(III)-rutin complex

Qadeer K. Panhwar and Shahabuddin Memon

Dr. M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro, 76080, Pakistan

E-mail: shahabuddinmemon@yahoo.com

Abstract: The article describes the synthesis and characterisation of the Cr(III)-rutin complex along with an estimate of its antioxidant activity. The complex was characterised using elemental analysis, UV-VIS, IR, conductance data, thermal, and gravimetric analyses. In the UV-VIS study, a bathochromic shift of approximately 98 nm indicates the formation of a rutin complex by more than one chelating site. The FT-IR spectra clearly show the formation of the Cr—O bond between rutin and Cr(III) at 494 cm⁻¹, while the thermal study shows the presence of eight coordinated water molecules in the complex. The gravimetric analysis quantitatively proves the presence of four chloride ions. From these data, the formula of the Cr(III)-rutin complex was deduced as [Cr₂(C₂₇H₂₈O₁₆)(H₂O)₈]Cl₄. Moreover, the antioxidant study of the complex was evaluated by using 2,2′-diphenyl-1-picrylhydrazyl (DPPH) free-radical, ferric-reducing, and phosphomolybdenum assays, which show that the complex has a higher antioxidant activity than rutin.

Keywords: chromium(III) – rutin – reducing power – chelation – antioxidant

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-013-0494-6

Chemical Papers 68 (5) 614–623 (2014)