ISSN print edition: 0366-6352
ISSN electronic edition: 1336-9075
Registr. No.: MK SR 9/7
ZnO nanoparticles in the synthesis of AB ring core of camptothecin
Selvaraj Mohana Roopan and Fazlur Rahman Nawaz Khan
Organic & Medicinal Chemistry Research Laboratory, Organic Chemistry Division, School of Advanced Sciences, VIT University, Vellore, India
Abstract: For the first time, synthesis of AB ring core of camptothecin synthons such as (2-chloroquinolin-3-yl)methanols (Va-Vg) using zinc oxide nanoparticles is reported. The desired attractive products were obtained in high yields, short reaction
time, using a simple work-up procedure with the purification of products by non-chromatographic methods.
Keywords: ZnO nanoparticles - camptothecin synthons - (2-chloroquinolin-3-yl)methanol
Full paper is available at www.springerlink.com.
Chemical Papers 64 (6) 812–817 (2010)
Tuesday, September 27, 2022