ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Conductometric sensor with calixarene-based chemosensitive element for the arginine detection

O. O. Soldatkin, S. V. Marchenko, O. V. Soldatkina, S. O. Cherenok, O. I. Kalchenko, O. S. Prynova, O. M. Sylenko, V. I. Kalchenko, and S. V. Dzyadevych

National Academy of Sciences of Ukraine, Kiev, Ukraine

E-mail: alex_sold@yahoo.com

Abstract: A possibility of the creation of conductometric chemosensor with calixarene-based sensitive element for arginine detection was evaluated. The surface of gold interdigitated electrodes of conductometric transducer was modified with calixarene. The optimal concentration of calixarene for preparation of chemosensitive element was determined to be 100 mg/ml. The basic analytical characteristics of the developed chemosensor were determined (sensitivity to arginine—37.5 μS/mM, limit of arginine detection 5 μM, linear range 0.005–150 μM, response time 150 s) and analyzed as regards its application for arginine determination. It was established for all types of developed sensors that they have good reproducibility of signals to arginine over one working day; the measurement error (RSD) did not exceed 5%. The selectivity of calixarene-based chemosensor to arginine was investigated as well as the selectivity of calixarene complexation with arginine compared with other amino acids.

Keywords: Chemosensor ; Calixarene ; Arginine ; Conductometric transducer 

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-018-0515-6

Chemical Papers 72 (11) 2687–2697 (2018)