ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Non-enzymatic glucose sensor of high sensitivity fabricated with direct deposition of Au particles on polyvinylferrocene film modified Pt electrode

Shveta Malhotra, Yijun Tang, and Pradeep K. Varshney

University of Wisconsin Oshkosh, Wisconsin, USA

E-mail: tangy@uwosh.edu

Abstract: In the present paper, highly sensitive non-enzymatic sensor was developed by simple method based on direct deposition of gold particles on polyvinylferrocene matrix modified Pt electrode (Au/PVF/Pt) for detection of glucose. The gold particles were generated from potassium tetrachloroaurate (III) (KAuCl₄) solution based on optimization of concentration of the solution and growth time of Au particles. The electrochemical characterization and electrocatalytic activities of the proposed sensor were studied with the help of cyclic voltammetry and chronoamperometry techniques. The Au/PVF/Pt sensor was evaluated on analytical parameters such as sensitivity, selectivity, stability, detection limits, repeatability, and reproducibility. As gold particles provide active sites towards oxidation of glucose, two wide linear ranges, 10–80 μM and 100–6 mM with ultra-sensitivities of 3236.3 and 730.3 μA mM⁻¹ cm⁻² respectively, were observed. Furthermore, limit of detection was calculated as 0.068 mM with fast response time of 2 s. Additionally, the sensor showed good repeatability and reproducibility with RSD of 3.03 and 2.14% respectively. The as-prepared Au/PVF/Pt sensor was able to show excellent stability and selectivity to glucose exclusively in the presence of other interfering species. Finally, the Au/PVF/Pt sensor could successfully detect glucose in various boxed juices samples. The results obtained from our method were compared to the commercial glucose meter. Hence, the applicability of Au/PVF/Pt sensor can be promising for determination of glucose in various fields such as food, biotechnology, and clinical diagnosis.

Keywords: Chronoamperometry ; Cyclic voltammetry ; Glucose sensor ; Non-enzymatic ; Polyvinylferrocene 

Full paper is available at www.springerlink.com.

DOI: 10.1007/s11696-019-00752-7

Chemical Papers 73 (8) 1987–1996 (2019)