ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Effect of microwave irradiation on the reactivity of chloroarenes in Suzuki—Miyaura reaction

V. Poláčková and Š. Toma

Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská dolina, 842 15 Bratislava, Slovakia

E-mail: polackova@fns.uniba.sk

Received: 18 May 2006  Revised: 18 July 2006  Accepted: 18 July 2006

Abstract: Simple catalytic systems for the Suzuki—Miyaura reaction of aryl chlorides under microwave conditions were tested. Microwave irradiation facilitated the reaction course. The catalyst, base, and solvent effect were studied and two reaction systems offered reasonable to high yields within a short time.

Keywords: cross-coupling reaction - Suzuki—Miyaura reaction - microwave irradiation - chloroarenes - palladium catalyst

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-006-0093-x

Chemical Papers 61 (1) 41–45 (2007)