ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Design and Economics of Industrial Production of Fructosyltransferase

K. Vaňková, M. Antošová, and M. Polakovič

Department of Chemical and Biochemical Engineering, Faculty of Chemical and Food Technology Slovak University of Technology, SK-812 37 Bratislava

E-mail: milan.polakovic@stuba.sk

Abstract: A production process of preparation FTase, a powdery purified enzyme, from Aureobasidium pullulans was designed. The process flowsheet consisted of unit operations needed for the aerobic cultivation of the cells and subsequent separation steps of the enzyme recovery from the cultivation medium and cell mass. An optimum schedule of operations was designed for the defined annual production capacity that minimized the number of equipment pieces and maximized the time of their usage. The evaluated mass and energy balances and calculated dimensions of the equipment formed the basis for the calculation of capital and operating cost of the production process. The profitability of the designed process was analyzed as a function of the price of the enzyme preparation.

Full paper in Portable Document Format: 596aa441.pdf

Chemical Papers 59 (6a) 441–448 (2005)