ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Effect of Ultrasound on One-Pot Conversion of Alcohols to Nitro and Azido Compounds

M. Mečiarová, Š. Toma, and P. Babiak

Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, SK-842 15 Bratislava

E-mail: mmeciarova@fns.uniba.sk

Received: 24 January 2003

Abstract: Synthesis of aliphatic nitro and azido compounds from corresponding alcohols under ultrasonic irradiation was studied. Ultrasonic irradiation of the reaction mixture ROH/NaNO₂/HCl allowed to shorten the reaction time and increase yields of aliphatic nitro compounds. Ultrasonic irradiation of the reaction mixture PhCH₂OH/NaN₃/PPh₃ resulted in formation of PhCH₂N₃ in yields comparable with those of the silent experiments. The next product was benzyl chloride and not benzylamine as was described in the literature.

Full paper in Portable Document Format: 582a104.pdf

Chemical Papers 58 (2) 104–108 (2004)