ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Isothiocyanates. XLIV. Preparation and properties of some substituted benzhydryl isothiocyanates

J. Kalamár, Ľ. Drobnica, K. Antoš, J. Surá, and D. Mravec

Department of Organic Technology, Slovak Technical University, 880 37 Bratislava

Abstract:  Synthesis of 2-, 3-, 4-, and 4,4/-substituted benzhydryl isothiocyanates with halo, methyl, methoxy, nitro, and isothiocyanato groups as substituents is described. The obtained i.r. spectral data indicate that jo-substituents in the substituted benzhydryl isothiocyanates similarly as in benzyl isothiocyanates affect v_as(NCS) so that a linear correlation with σ_m and σ_p values is valid. The reactivity of — NCS group with OH- ions and — NH₂ group of glycine respectively was studied spectrophotometrically. The obtained reaction rates of glycine addition do not point to a possibility of this correlation.

Full paper in Portable Document Format: 286a840.pdf

Chemical Papers 28 (6) 840–847 (1974)