ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis of cinnamic acid-derived 4,5-dihydrooxazoles

Juraj Kronek, Tomáš Nedelčev, Marcel Mikulec, Angela Kleinová, and Jozef Lustoň

Polymer Institute, Slovak Academy of Sciences, Centre of Excellence-GLYCOMED, Dúbravská cesta 9, 845 41, Bratislava, Slovakia

E-mail: upolkron@savba.sk

Abstract: A range of cinnamic units containing 4,5-dihydrooxazoles was prepared using two different synthetic routes. The first method was based on the transformation of substituted cinnamic or benzoic acids to 2-styryl-4,5-dihydrooxazoles. Several derivatives containing phenolic groups were prepared in this manner. The second approach consisted of a reaction between the 4,5-dihydrooxazole moiety and double bond-containing compounds. These compounds contain two or more reactive centres capable of providing polymerisations and also organic reactions.

Keywords: cinnamic acid derivatives – 4,5-dihydrooxazole – conjugated unsaturated bond – 2-oxazolines

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-013-0405-x

Chemical Papers 67 (11) 1424–1432 (2013)