ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

The King Reaction in a Series of  γ - and δ-Lactone

G. S. Melikyan, A. A. Akhnazaryan, A. A. Avetisyan, J. Halgaš, and P. Foltínová

Department of Organic Chemistry, Faculty of Chemistry, Yerevan State University, 375049 Yerevan

Abstract: The King reaction of α,β-unsaturated γ - and δ-lactones having a reactive methyl group in position β was studied for the first time. These compounds, reacting with pyridine derivatives, afforded quaternary pyridinium salts which were tested for antimicrobial activity. An α,β-unsaturated α-cyano ester, an open-chain analogue of the above-mentioned lactones, was also used in the reaction.

Full paper in Portable Document Format: 464a269.pdf

Chemical Papers 46 (4) 269–271 (1992)