ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Quantitative relations between structure and pesticidal activity of new pyridazinyl thiophosphates

P. Zahradník, V. Konečný, D. Loos, J. Žúžiová, and J. Leška

Department of Organic Chemistry, Faculty of Natural Sciences, Comenius University, CS-84215 Bratislava

Abstract:  Quantitative structure—activity relationships in the series of 1,6-dihydro-4-pyridazinyl thiophosphates were investigated by Hansch and Free—Wil­son methods. Insecticidal, acaricidal, and fungicidal activities were cor­related with experimental physicochemical data and topological steric index. Compounds were classified into active and inactive groups by the cluster analysis. The quantitative activity contributions of the substituents were obtained by the Free—Wilson method.

Full paper in Portable Document Format: 434a537.pdf

Chemical Papers 43 (4) 537–546 (1989)