ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Easy route to 2-O-substituted D-xylose derivatives

J. Hirsch and P. Kováč

Institute of Chemistry, Slovak Academy of Sciences, 809 33 Bratislava

Abstract: The synthesis of crystalline, hitherto unknown, methyl 3,5-O-benzylidene-α- and -ß-D-xylofuranosides / and II is described. By methylation of the foregoing furanosides and splitting of the blocking benzylidene groups by hydrogenolysis methyl furanosides of 2-0-methyl-D-xylose were obtained through a sequence by two steps shorter than is known in the literature. Catalytic hydrogenolysis of I and II afforded methyl α- and ß-D-xylofuranosides in high yields.

Full paper in Portable Document Format: 276a816.pdf

Chemical Papers 27 (6) 816–820 (1973)