ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

An efficient and novel one-pot synthesis of 2,4,5-triaryl-1H-imidazoles catalyzed by UO₂(NO₃)₂·6H₂O under heterogeneous conditions

Vardhineedi Sri Venkata Satyanarayana and Amaravadi Sivakumar

Chemistry Division, School of Advanced Sciences, VIT University, Vellore, 632014 India

E-mail: profaskumar09@gmail.com

Abstract: An efficient, convenient, and novel one-pot method of 2,4,5-triaryl-1H-imidazoles synthesis using benzil, arene carbaldehydes, and ammonium acetate, catalyzed by uranyl nitrate hexahydrate [UO₂(NO₃)₂·6H₂O] supported on acidic alumina and resulting in good to excellent yields under heterogeneous conditions, is reported. Formation of a reactants-catalyst complex was confirmed by UV-VIS spectral data. Antibacterial (MIC) and antioxidant activity of the synthesized compounds was also studied.

Keywords: 2,4,5-triaryl-1H-imidazoles – uranyl nitrate hexahydrate – heterogeneous system – antimicrobial activity – antioxidant activity

Full paper is available at www.springerlink.com.

DOI: 10.2478/s11696-011-0028-z

Chemical Papers 65 (4) 519–526 (2011)