ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Synthesis of thiohydantoin and rhodanine derivatives from 4-substituted cinnamoyl isothiocyanates

M. Dzurilla and E. Demjánová

Department of Organic Chemistry, Faculty of Natural Sciences, P. J. Šafárik University, 041 67 Košice

Abstract:  Synthesis of 3-(4-substituted cinnamoyl)-2-thiohydantoins and 3-(4-substituted cinnamoyl)rhodanines bty cyclization of 4-substituted cinnamoyl isothiocyanates with glycine and thioglycolic acid, respectively in acid medium is described. The structures of the synthesized compounds are proved by infrared and ultraviolet spectra.

Full paper in Portable Document Format: 285a693.pdf

Chemical Papers 28 (5) 693–696 (1974)