ISSN print edition: 0366-6352 ISSN electronic edition: 1336-9075 Registr. No.: MK SR 9/7 Published monthly

Solvolysis of O-acyl-10-hydroxy-10,11-dihydro-indeno[1,2-c]isoquinolin-5,11-diones

T. Kučerová, J. Mollin, and J. Michalský

Department of Inorganic and Physical Chemistry, Faculty of Natural Sciences, Palacký University, 771 46 Olomouc

Abstract: The rate of the solvolysis of O-acyl-10-hydroxy-10,11-dihydroinde- no[1,2-c]isoquinolin-5,ll-diones and of the corresponding p-nitrophenyl es­ ters under neutral conditions has been determined. It follows from the comparison of the rates as well as from the pK values of the corresponding acids and the activation entropies found for the process of the solvolysis that the reaction, affected also by steric effects, is governed by the S_N2 mechanism.

Full paper in Portable Document Format: 333a404.pdf

Chemical Papers 33 (3) 404–409 (1979)