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Benzothiazole compounds. XVII. 2-Alkyl- and 2-aralkylsulfonylbenzothiazoles and their antimicrobial activity

V. Sutoris, P. Foltínová, and A. Gáplovský

Department of Organic Chemistry, Faculty of Natural Sciences, Komenský University, 816 31 Bratislava

 

Abstract: By oxidation of 2-alkylthio-, 6-nitro-2-alkylthio-, and 2-aralkylthiobenzothiazoles the appropriate sulfones were prepared which showed good antibacterial, antifungal, and antimycobacterial activities. With some derivatives good activity was found also on Mycobacterium fortuitum. A correlation between the biological activity of the prepared compounds and their partition coefficients was proved in the system of octane-methanol.

Full paper in Portable Document Format: 343a404.pdf

 

Chemical Papers 34 (3) 404–412 (1980)

Tuesday, February 07, 2023

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